Landmark

Bregma

The skull landmark that anchors brain coordinates

Definition
The anatomical landmark on the skull where the coronal and sagittal sutures intersect. It is the zero-reference point for anterior-posterior and medial-lateral stereotaxic coordinates in rodent neuroscience.
Suture Intersection
Where coronal and sagittal skull sutures meet
AP Zero Point
Defines the origin for anterior-posterior measurements

Bregma as the Coordinate Origin

Bregma is the origin point of the stereotaxic coordinate system. During surgery, it is visible as the intersection of skull suture lines. During post-hoc analysis, PanoBrain's atlas registration maps each section back to its position relative to Bregma. That mapping enables:

  • Precise AP-level identification of each scanned section
  • Comparison of the same brain region across different animals
  • Correlation of histological findings with surgical injection coordinates

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