Unlock Molecular Insights at the Single-Molecule Level
The CorTector™ CX-B Series brings advanced fluorescence correlation spectroscopy (FCS) and single-molecule analysis directly to your research microscope. Designed as an upgrade module, it bridges the gap between live-cell imaging and molecular-scale investigation—delivering powerful quantitative and qualitative insights into biological processes.
Key Capabilities
Oligomerization Analysis
Characterize molecular complexes and higher-order assemblies.
Concentration Measurement
Detect molecular or nanoparticle concentrations ranging from 10 pM – 500 nM.
Diffusion & Hydrodynamics
Accurately determine diffusion coefficients and hydrodynamic radii (Rhd < 100 nm).
Molecular Interactions
Analyze up to four molecular species simultaneously, including binding kinetics and equilibrium dissociation constants (KD values).
Advanced Single-Molecule Techniques
Built on solution-based fluorescence (no immobilization required), the CX-B Series integrates cutting-edge approaches including:
- ALEX smFRET (Alternating Laser Excitation Single-Molecule FRET)
- Coincidence Analysis
- Conformational state analysis and transition kinetics at the μs–ms timescale
These methods enable direct observation of structural dynamics that drive biological function.
Flexible Integration with Your Microscope
The CX-B Series is designed to seamlessly interface with any research-grade fluorescence microscope, including:
- Widefield
- Confocal
- Multiphoton
- TIRF
- STED
- FLIM
- Light sheet microscopy
This versatility makes it the ideal tool to expand the capabilities of your existing imaging system.
Modular System Architecture
The platform combines precision hardware and intuitive software:
- Laser Source Module – Up to five selectable lasers (375–638 nm) with optional alternating excitation (1 Hz–6 kHz).
- Optical Path Module – Confocal light paths with manual or automated pinhole calibration.
- Detection Module – 1–4 APD channels with single-photon data acquisition.
- Software Suite – Tools for correlation, burst, and photon counting histogram (PCH) analysis.
- High-Performance Computing – Optional workstation for data-intensive applications.
Why Choose CorTector™ CX-B?
- Scalable – Upgrade from basic to advanced configurations as research needs evolve.
- Versatile – Compatible with a wide range of microscopes and imaging modalities.
- Cutting-Edge – Incorporates the latest single-molecule fluorescence analysis techniques.
- Reliable Partner – Backed by LightEdge Technologies’ expertise in advanced optical instrumentation.