Modern scientific cameras use column-parallel ADC architectures, where each column of pixels has its own converter, enabling simultaneous readout across the sensor. ADC bit depth (typically 12-16 bits) determines the number of digitization levels. ADC speed (in megasamples/second) limits the maximum frame rate. ADC noise contributes to the camera's total read noise.
The ADC should have enough bit depth to fully digitize the sensor's dynamic range. If dynamic range (well depth / read noise) exceeds 2N, the ADC is the bottleneck — it discards information the sensor captured.